Ozone Therapy


Ozone is an unstable gas molecule made up of three oxygen atoms. It is located in the outermost layer of the atmosphere and enables the continuation of life by preventing the radiation from the sun. Ozone gas was discovered in the 18th century. Over the years, the importance of ozone has been understood and ozone has been used in industry and health. Ozone is a powerful oxidative molecule and has a lethal effect on bacteria. For this feature, it has been used in various fields for years.

What are Ozone Application Methods?

Major Autohemotherapy

It is the most common application method. In this method, an amount of blood taken from the patient’s vein (50-120ml) is taken up in a sterile tube ozone resistant. The appropriate dose of ozone – oxygen mixture is given to this blood and after the mixture is provided, it is given back to the body in the same way. Major autohemotherapy is the main application method and takes about 20 minutes.

Minor Autohemotherapy

A small amount of blood is mixed with ozone in a syringe and injected intramuscularly.

Injection into the Joint

In this method, 3-5 injection gases (ozone-oxygen mixture) are applied to the joints with calcification intermittently.

Local Application

Ozone-oxygen injection is applied to myofascial trigger points (grip) and painful trigger points in the muscle. Generally, 1-1-3 application is sufficient. Similar application can be made in tendon rheumatism. Since it is a little painful, it is not preferred.

Paravertebral Ozone Injection

Paravertebral ozone therapy is performed by injecting ozone-oxygen mixture into the muscles on both sides of the spine in lumbar and neck hernias. The application is a 30-second process and is performed in 1 to 3 times a week depending on the situation of the patient. In most patients, a 10-session injection course is sufficient. In simple cases, up to 5 sessions and in very severe cases up to 20 sessions can be performed. During the injection, although there is a varying degree of pain depending on the patient, it resolves within a few minutes. Paravertebral ozone injection gives extremely bright results in waist and neck hernias and can provide a very rapid recovery.

Intradiscal Application

It is a special application where ozone-oxygen is administered in the form of injection with long needles into the disc with fluoroscopy or tomography in the operating room environment in patients with lumbar hernia. It is an effective treatment by reducing the size of the hernia. It is applied by pain specialists. The results are successful, but there may be few complications. Other disadvantages are that the patient receives radiation and it is expensive.


It is mostly preferred in non-healing bed and diabetes wounds and gangrenes. The patient’s body part is placed in a special bag and the ozone-oxygen mixture is given into this bag and the healing effect is obtained by ensuring the contact of the gas and the wound.

Rectal Ozone Application (Insufflation)

Rectal application of ozone in patients who cannot be administered intravenously.

Ozonated Water

It is done with ozonized isotonic saline. In particular, infected wounds are treated by washing with this water.

Ozonated Oil

Ozonized oil is used in skin lesions.

Ozone Sauna

Mostly used for cosmetic purposes.

Conditions where ozone is used

  • Musculoskeletal System
  • Circulatory System
  • Eye Diseases
  • Cosmetic Applications
  • Slimming

Diseases in which ozone therapy is used

  • Diabetes
  • Rheumatoid arthritis
  • Circulatory disorder
  • Gout
  • Candidiasis
  • Alzheimer’s
  • Parkinson’s
  • Dementia
  • Emphysema, COPD, acute respiratory stress
  • Retinitis pigmentosa, cataracts, glaucoma, age-related macular degeneration
  • Hypertension, venous insufficiency, peripheral arterial disease, venous
  • Herpes simplex, herpes zoster, AIDS, hepatitis A, B, C, human papilloma virus
  • Cerebral palsy
  • Allergic diseases
  • Chronic fatigue syndrome
  • Systemic lupus erythematosus
  • Crohn’s disease
  • Intestinal diseases
  • Avn disease
  • Nonhealing chronic wounds
  • Diabetic foot sores
  • Complementary therapy in cancer treatment


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